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Alcohol Denat. (SD Alcohol 39-C)-Aqua (Water) Parfum(Fragrance)

Alpha-isomethyl ionone

Alpha-isomethyl ionone is a synthetically made and naturally occurring organic compound found in Brewer's yeasts or the species known as Saccharomyces cerevisiae (wiki). It has a floral-woody scent and is used in many perfumes and personal care products for its aromatic similarity to violet (https://ecostore.com/au/ingredients/used-with-care/alpha-isomethyl-ionone ). alpha-Isomethyl-ionone is a thoroughly evaluated and commonly used fragrance ingredient.It has been identified by European Union scientific bodies as a potential skin sensitizer. This means that alpha-isomethyl-ionone has the potential to cause a skin reaction (such as red, bumpy, or itchy skin). These reactions can be hard to identify, and they are just as likely to be caused by natural ingredients as synthetic ingredients (https://fragranceconservatory.com/ingredient/alpha-iso-methyl-ionone). The Flavor and Extract Manufacturers Association Expert Panel has reviewed the safety of Alpha-Isomethyl Ionone and determined that it was Generally Recognized as Safe (GRAS ) for use as a flavoring substance (https://cosmeticsinfo.org/ingredient/alpha-isomethyl-ionone-0).

Amyl cinnamal

 Amyl Cinnamal, also called alpha-amyl cinnamic aldehyde, is a pale yellow liquid with a floral smell suggestive of jasmine. In cosmetics and personal care products, Amyl Cinnamal is used in the formulation of bath products, bubble baths, body and hand products, and shampoos (https://cosmeticsinfo.org/ingredient/amyl-cinnamal). The fragrance chemical amyl cinnamal is classified as a frequent and well-recognized allergen in CosIng, the European Commission database for information on cosmetic substances and ingredients. CosIng has also is restricted this ingredient for use in cosmetic products in the European Union due to its allergenic properties.The Swedish Society for Nature Conservation (SSNC) also lists amyl cinnamal as allergenic (https://www.curiouschloride.com/substances/amyl-cinnamal/).

Amyl-cinnamyl Alcohol

Amylcinnamyl Alcohol, also called alpha-amyl cinnamic alcohol, is a colorless to slightly yellow liquid with a light floral odor. In cosmetics and personal care products, it is used as a fragrance ingredient in a wide variety of products including bath products, soaps and detergents, perfumes and colognes, skin care products and hair care products (https://cosmeticsinfo.org/ingredienta/amylcinnamyl-alcohol-0). Consumers should avoid eye contact, consumption or inhalation of alpha-Amylcinnamyl alcohol. In minor doses, where the chemical is mixed with other ingredients, such as when part of a perfume, the risk may be reduced, but consulting a doctor is always best( https://www.chemservice.com/news/2014/06/what-do-you-know-about-alpha-amylcinnamyl-alcohol/).

Anise Alcohol

Anise Alcohol, also called anisyl alcohol, is a colorless to slightly yellow liquid having a pleasant floral odor. In cosmetics and personal care products, Anise Alcohol is used in skin care products and is used as a fragrance ingredient. Anise Alcohol is found naturally in the plant Pimpinella anisum, also called anise or sweet cumin. It is also made synthetically.

Benzyl Alcohol

Benzyl Alcohol is derived from fruit, comes in the form of a colorless liquid, and has a slightly sweet scent. As a multifunctional ingredient, you can spot benzyl alcohol on the ingredient label of many different skincare, cosmetic, and personal products, such as moisturizers, lip balms, face washes, and even makeup. 

Here are a few key ways benzyl alcohol helps your products work more effectively:

Preserves the product: Benzyl alcohol allows products to be bottled in larger packages designed for more than one use.

Stabilizes the formula: the ingredient also acts as a stabilizing agent against the oxidative breakdown of the product, which means it allows your products to work more effectively for a longer period of time.

Has antioxidant activity: benzyl alcohol also has antioxidant properties, and antioxidants protect against free-radical damage.

Dissolves ingredients: Benzyl alcohol is also shown to function as a solvent and helps to dissolve other ingredients in a product's formula.

Decreases viscosity: Studies show benzyl alcohol also improves viscosity, which allows products to flow more easily.

Imparts a nice scent: As an aromatic alcohol, benzyl alcohol is naturally fragrant and gives off a slightly sweet scent.

In general, benzyl alcohol is safe to use by anyone who does not have a true contact allergy to it. 

https://www.byrdie.com/benzyl-alcohol-for-skin-4774552

Benzyl Benzoate

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. Benzyl benzoate exerts toxic effects on the nervous system of the parasite, resulting in its death. It is also toxic to mite ova, though its exact mechanism of action is unknown. In vitro, benzyl benzoate has been found to kill the Sarcoptes mite within 5 minutes.

https://go.drugbank.com/drugs/DB00676

Benzyl Cinnamate

Benzyl Cinnamate has a sweet balsam floral fruity cherry scent (https://www.perfumersworld.com/view.php?pro_id=2SQ00056). It can be found in ylang ylang, cumin and balsam. Benzyl cinnamate is a thoroughly evaluated and commonly used fragrance ingredient. It has been identified by European Union scientific bodies as a potential skin sensitizer. This means that benzyl cinnamate has the potential to cause a skin reaction (such as red, bumpy, or itchy skin). These reactions can be hard to identify, and they are just as likely to be caused by natural ingredients as synthetic ingredients (https://fragranceconservatory.com/ingredient/benzyl-cinnamate).

Benzyl Salicylate

Benzyl salicylate is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics as a fragrance additive or UV light absorber. It appears as an almost colorless liquid with a mild odor described as "very faint, sweet-floral, slightly balsamic" by some, It occurs naturally in a variety of plants and plant extracts and is widely used in blends of fragrance materials (https://en.m.wikipedia.org/wiki/Benzyl_salicylate).

Cinnamal

Cinnamal, also called cinnamaldehyde, is a yellow oily liquid that gives cinnamon its spice. In cosmetics and personal care products, Cinnamal is used in the formulation of aftershave lotions, bath products, dentifrices, lipsticks, moisturizers, and mouthwashes and breath fresheners (https://cosmeticsinfo.org/ingredient/cinnamal-0)

Cinnamyl Alcohol

Cinnamyl Alcohol is a naturally occurring fragrance compound found in the bark of cinnamon trees, as well as in the leaves of the tea-tree, and hyacinth and daffodil flowers. It can also be produced synthetically (https://cosmeticsinfo.org/ingredient/cinnamyl-alcohol-0). Cinnamyl alcohol and its esters are used in perfumery. It is also used in multicolor printing, in animal repellents, and insect attractants (https://onlinelibrary.wiley.com/doi/abs/10.1002/0471238961.0309141405091205.a01.pub2).

Citral

 Citral is a unsaturated aldehyde, commonly known and prefer for its distinct, acceptable, and lemon-like pleasant odor (Berk, 2016). Citral is a main component of citrus fruit's peel oil. It is especially found in orange peel. Citral has been applied to food, cosmetics, and beverages as a natural ingredient for its passionate lemon aroma and flavor. Essential oils, which presenting citral have been demonstrated to show antimicrobial, antifungal, and antiparasitic characteristics, accomplishing citral a natural preservative (Zeng et al., 2015) (https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/citral).

Citronellol

Citronellol is a volatile fragrance chemical extracted from geranium, rose, and other plants, citronellol has a characteristic grassy, citrus-like scent (https://www.paulaschoice.com/ingredient-dictionary/fragrance-synthetic-and-fragrant-plant-extracts/citronellol.html).  They often have a strong scent and may protect the plants that produce them by deterring herbivores and by attracting predators and parasites of herbivores. Citronellol is a naturally occurring ingredient used in skincare and cosmetic formulations to improve the scent of products. It is also often used in perfume formulations to help enhance the intensity of other scent ingredients. In perfumes, citronellol functions as a fragrance enhancer since it has the ability to enhance the aromas of floral types especially rose. In the skincare industry, citronellol is prominently used as a fragrance ingredient for cosmetics and skincare products. Research suggests that the topical application of citronellol has low permeability and potency, meaning that it doesn’t penetrate deeply into the skin or isn’t absorbed into the skin. Unlike many essential oil components, citronellol doesn’t cause irritation. While this is the case, it can cause sensitivity and irritation in some skin types. The low likelihood of irritation makes citronellol an ideal ingredient to improve the scent of products, such as shampoos, lotions, creams, shaving creams, and bath products. It is one of the active components of citronella oil insect repellents and citronella candles. In fact, citronella has been registered as a gentle, plant-based insect repellent in the U.S. since 1948. Citronella insect repellents have even been shown to repel dangerous Aedes aegypti mosquitoes, which are capable of spreading dengue fever and the Zika virus. The United States Food and Drug Administration considers citronellol as generally recognized as safe for direct addition to food. The Cosmetic Ingredient Review Expert Panel defers review of individual fragrance ingredients to the International Fragrance Association program unless the ingredient has significant uses other than as a fragrance.The safety of citronellol has been evaluated by the Research Institute for Fragrance Materials Expert Panel. Based on the evaluation, citronellol is restricted in fragrances because of potential sensitization. However, the degree to which citronellol can cause an allergic reaction in humans is disputed. As mentioned above, citronellol has low permeability when applied to the skin, which means it is not absorbed into the deeper layers of skin. However, when products containing citronellol are applied to the skin, a problem arises when citronellol is exposed to air. This exposure causes the unstable citronellol molecule to oxidize, which is believed to trigger aggravation on the skin. Due to the possibility of an allergic reaction, those with sensitive skin should try to avoid citronellol or perform a patch test with any product containing this ingredient.

Coumarin

Coumarins exhibited antitumor activities at different stages of cancer formation through various mechanisms, such as blocking cell cycle, inducing cell apoptosis, modulating estrogen receptor, or inhibiting the DNA-associated enzymes, such as topoisomerase (Emami and Dadashpour, 2015). 

From: Value-Added Ingredients and Enrichments of Beverages, 2019

Coumarins are phenolic substances composed of fused benzene and α-pyrone rings. At least 1300 different coumarins have been identified. Coumarins have antithrombotic, antiinflammatory, and vasodilatory activities. Warfarin is the most popular one and it is used as an oral anticoagulant and rodenticide. Coumarins may also have antiviral effects and are highly toxic in rodents. Some of the coumarins compounds have antimicrobial effects such as an inhibitory effect against C. albicans and thus can be used to cure vaginal candidiasis. In addition, coumarins can induce macrophages which exert a negative effect on bacterial infections. 

https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/coumarin

Eugenol

Eugenol, also called clove oil, is an aromatic oil extracted from cloves that is used widely as a flavoring for foods and teas and as an herbal oil used topically to treat toothache and more rarely to be taken orally to treat gastrointestinal and respiratory complaints. Eugenol in therapeutic doses has not been implicated in causing serum enzyme elevations or clinically apparent liver injury, but ingestions of high doses, as with an overdose, can cause severe liver injury (https://pubchem.ncbi.nlm.nih.gov/compound/Eugenol). Oil of cloves or eugenol is commonly used by dentists because it is antiseptic and anti-inflammatory. They often apply it to the gums to kill germs and relieve the pain of dental surgery such as tooth extractions, fillings, and root canals (https://www.motherearthliving.com/plant-profile/eugenol).

Farnesol

Farnesol is a colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery (https://pubchem.ncbi.nlm.nih.gov/compound/Farnesol#section=Use) Farnesol has been identified as an antioxidant (https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/farnesol).

Geraniol

Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including rose oil, citronella, lemongrass, lavender, and other aromatic plants. It is emitted from the flowers of many species of plants and is commonly used by the food, fragrance, and cosmetic industry. Geraniol has demonstrated a wide spectrum of pharmacological activities including antimicrobial, anti-inflammatory, antioxidant, anti-cancer, and neuroprotective to name a few. Interestingly, geraniol has also been shown to sensitize tumour cells to commonly used chemotherapies including [DB00544] and [DB01248] and represents a promising cancer chemopreventive agent. Due to its anticancer effects, geraniol has been found to be effective against a broad range of cancers including breast, lung, colon, prostate, pancreatic, skin, liver, kidney and oral cancers. These pharmacologic effects are clinically important as geraniol is classified as generally-recognized-as-safe (GRAS) by the Flavor and Extract Manufacturers Association (FEMA) and the Food and Drug Administration (FDA) of the United States. Sensitivity to geraniol may be identified with a clinical patch test. https://pubchem.ncbi.nlm.nih.gov/compound/Geraniol

Hexyl Cinnamyl

Hexyl cinnamal (also known as hexyl cinnamic aldehyde) is a pale yellow to colourless liquid. It is a synthetic organic compound that resembles the naturally occurring, spicy cinnamic aldehyde, but it possesses a subtler, floral character (Lush Fresh Handmade Cosmetics)

Hydroxycitronellal

Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley. Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially available products are restricted by the International Fragrance Association (IFRA) to contain only 0.1-3.6%.

(https://go.drugbank.com/drugs/DB14187)

Isoeugenol

Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry. Allergic reactivity to Isoeugenol may be identified with a patch test. It derives from a guaiacol, which is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Isoeugenol is one of several phenolic compounds responsible for the mold-inhibiting effect of smoke on meats and cheeses.

https://pubchem.ncbi.nlm.nih.gov/compound/Isoeugenol

https://pubchem.ncbi.nlm.nih.gov/compound/guaiacol

https://en.m.wikipedia.org/wiki/Isoeugenol

Butylphenyl Methylpropional

Butylphenyl methylpropional is an aldehyde, which is a family of ingredients that can either be natural or synthetic. Rose, citronella, cinnamon bark, and orange rind all contain natural aldehydes. Aldehydes can also boost the projection of a scent, or its sillage. Sometimes referred to as ‘lift,’ sillage is how far a scent travels away from the wearer. Butylphenyl methylpropional functions as a fragrance ingredient due to its strong floral scent. It is used in aftershave lotions, bath products, bubble baths, cleansing products, hair care products, moisturizers, perfumes and colognes, shampoos, and skincare products. Butylphenyl methylpropional is having a low risk of sensitization, some people may have an allergy to the ingredient.

(https://thedermreview.com/butylphenyl-methylpropional/)

Limonene

Limonene is a chemical found in the rind of citrus fruits, such as lemons, limes, and oranges. It is especially concentrated in orange peels, comprising around 97% of this rind’s essential oils (2Trusted Source). Limonene is one of the most common terpenes found in nature and may offer several health benefits. It has been shown to possess anti-inflammatory, antioxidant, anti-stress, and possibly disease-preventing and anti-cancer properties. Limonene is a popular additive in foods, cosmetics, cleaning products, and natural insect repellants. For example, it’s used in foods like sodas, desserts, and candies to provide a lemony flavor. Due to its strong aroma, limonene is utilized as a botanical insecticide. It’s an active ingredient in multiple pesticide products, such as eco-friendly insect repellents. Other household products containing this compound include soaps, shampoos, lotions, perfumes, laundry detergents, and air fresheners. Additionally, limonene is available in concentrated supplements in capsule and liquid form. These are often marketed for their supposed health benefits.This citrus compound is also used as an aromatic oil for its calming and therapeutic properties.

(https://www.healthline.com/nutrition/d-limonene#what-it-is)

Linalool

Like most botanical terpenes, Linalool is not specific to any one plant. You've no doubt encountered linalool if you've ever smelled lavender, either fresh, dried, or in the form of an essential oil. Linalool can be found in upwards of 200 plants, ranging from:  

Lamiaceae (lavender, mints, scented herbs)，Lauraceae (laurels,cinnamon, rosewood)，Rutaceae (citrus fruits)，FungiBirch trees. Linalool has a floral aroma similar to lavender with a touch of spiciness that lends to its many commercial applications in creams and oils. Linalool is an Anti-Inflammatory and Pain Reducer: Linalool is useful for dampening overractive responses to injury or sickness; an Anti-Epileptic:  Linalool is "very powerful in it's anticonvulsant quality", a stress Reducer: Linalool inhalation has been shown to act as an anxiolytic (anxiety reducer) and may boost immune system performance; a Vampire Deterrent: Linalool can deter mosquitos with 93% efficiency;a Sedative: Linalool can improve sleep and increase energy the following morning; an Anti-Microbial Modulator: Linalool may improve anti-microbial properties. Linalool can have cytotoxic effects by inducing cells to undergo apoptosis and triggering cell death. The majority of studies pertaining to the monoterpenoid linalool are typically focused on its capacity to suppress microorganisms, with few having endeavored to research aspects of its ANTI-CANCER activity. Linalool offers tremendous potential in terms of treating cancer and immunity. We believe that this substance can substantially ENHANCE TUMOR TREATMENTS and provide novel starting points for FUTURE CANCER RESEARCHES

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde

Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, also called HMPCC, is a clear, colorless liquid with a delicately sweet, light, floral odor. In cosmetics and personal care products, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde is used in the formulation of aftershave lotions, bath products, bubble baths, hair conditioners, moisturizers, perfumes and colognes, skin care products and suntan products. Hydroxyisohexyl 3-cyclohexene carboxaldehyde, also known as Lyral, is a fragrance ingredient identified as the cause of contact allergic reactions in 2-3% of eczema patients undergoing patch testing. Lyral has been included in the standard patch test series in many clinics due to its importance as an allergen. 

https://cosmeticsinfo.org/ingredient/hydroxyisohexyl-3-cyclohexene-carboxaldehyde-0

https://pubmed.ncbi.nlm.nih.gov/14531869/

Methyl-2-Octynoate

Methyl 2-octynoate, also known as fema 2729 or folione, belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid. Methyl 2-octynoate is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. This chemical is used as a fragrance in various cosmetics and as a food additive for flavor. It came from food and animal sources and it is naturally in our bodies.(https://hmdb.ca/metabolites/HMDB0031302)

Evernia furfuracea (treemoss) Extract

Treemoss extract is a naturally derived ingredient, extracted from tree moss that typically grows on pine and fir trees. It’s added to fragrances to give them a woodsy note. Treemoss extract is made up of a number of different chemical components—it’s not just one substance. Treemoss extract is a thoroughly evaluated and commonly used fragrance ingredient. It has been identified by European Union scientific bodies as a potential skin sensitizer. This means that treemoss extract has the potential to cause a skin reaction (such as red, bumpy, or itchy skin). These reactions can be hard to identify, and they are just as likely to be caused by natural ingredients as synthetic ingredients. (https://fragranceconservatory.com/ingredient/treemoss-extract)

Butyl methoxydibenzoylmethane

It is used in the formulation of SUN PROTECTION PRODUCTS, as well as bath, skin, cleansing, hair, nail and fragrance products. In the United States, when this ingredient is used in SUN PROTECTION PRODUCTS, it will be listed on the label as Avobenzone.

THE SCIENCE & SAFETY BEHIND YOUR FAVORITE PRODUCTS

Ethylhexyl Methoxycinnamate

Ethylhexyl Methoxycinnamate:

A clear, oil-soluble, "cosmetically-elegant" liquid that is the most commonly used chemical sunscreen. It absorbs UVB radiation (at wavelengths: 280-320 nm) with a peak protection at 310nm. It only protects against UVB and not UVA rays (the 320-400 nm range) – so always choose products that contain other sunscreens too. It is not very stable either, when exposed to sunlight, it kind of breaks down and loses its effectiveness (not instantly, but over time - it loses 10% of its SPF protection ability within 35 mins). Ethylhexyl  is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US) (INCI).

Ethylhexyl salicylate

A colorless to light yellowish oily liquid that works as a UVB (280-320nm) sunscreen filter with a peak absorbance at 306 nm. It's not a strong filter in itself, it's always used in combination with other sunscreen agents to further enhance the SPF and to solubilize other solid UV filters. It has a good safety profile and is allowed to be used at a max concentration of 5% both in the US and in Europe (10% is allowed in Japan). https://incidecoder.com/ingredients/ethylhexyl-salicylate

CI 19140 (Yellow 5)

A pyrazole aniline dye widely used to color foods, cosmetics, drugs, and textiles. Its use has been linked to hives and other allergic-type reactions in some individuals. (https://medical-dictionary.thefreedictionary.com/Yellow+5)

CI 14700 (Red 4)

C.I. 14700 is a red azo dye once used as a food dye. As a food additive, it has the E number E125. It usually used as a disodium salt. In the United States, it is not permitted for use in food or ingested drugs and may only be used in externally applied drugs and cosmetics. An exception was added in 1965 to allow its use in the coloring of maraschino cherries, which were considered mainly decorative and not a foodstuff. This exception was repealed in 1976 due to mounting safety concerns. In the European Union, it is not permitted as a food additive. https://en.m.wikipedia.org/wiki/Scarlet_GN

CI 17200 (Red 33)

Red 33 also known as Acid Red 33 or simply Red 33 is a red azo dye used as a colorant in mouthwashes, dentifrices, cosmetics, and hair dyes. It is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics. https://en.m.wikipedia.org/wiki/D%26C_Red_33

https://www.ewg.org/skindeep/ingredients/701803-DC_Red_No_33_CI_17200/)

CI 42090 (Blue 1)

 is a synthetic organic compound used primarily as a blue colorant for processed foods, medications, dietary supplements, and cosmetics. It has the appearance of a blue powder and is soluble in water and glycerol, with a maximum absorption at about 628 nanometers. It is one of the oldest FDA-approved color additives and is generally considered nontoxic and safe. (https://en.m.wikipedia.org/wiki/Brilliant_Blue_FCF)