Coumarin
Coumarins exhibited antitumor activities at different stages of cancer formation through various mechanisms, such as blocking cell cycle, inducing cell apoptosis, modulating estrogen receptor, or inhibiting the DNA-associated enzymes, such as topoisomerase (Emami and Dadashpour, 2015).
From: Value-Added Ingredients and Enrichments of Beverages, 2019
Coumarins are phenolic substances composed of fused benzene and α-pyrone rings. At least 1300 different coumarins have been identified. Coumarins have antithrombotic, antiinflammatory, and vasodilatory activities. Warfarin is the most popular one and it is used as an oral anticoagulant and rodenticide. Coumarins may also have antiviral effects and are highly toxic in rodents. Some of the coumarins compounds have antimicrobial effects such as an inhibitory effect against C. albicans and thus can be used to cure vaginal candidiasis. In addition, coumarins can induce macrophages which exert a negative effect on bacterial infections.
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/coumarin
Coumarin 在不同階段的癌症有不同方式的抗腫瘤作用， 能阻擋細胞生命循環，引發細胞自然死亡，調變Estrogen受體，DNA相關酵素，即是topoisomerase。Coumarin 有防血栓，防炎，擴張血管作用。Wolverine。。。。。Warfarin 就是最常見的Coumarin, 它是口服抗血凝劑及殺鼠劑。Coumarins也可能有抗病毒功能。有某種Coumarins有抗菌例如C.albicans的功能，因此能用來治療陰道念珠菌感染。它亦能誘導巨噬細胞抑制細菌感染。
The following perfumes contain Coumarin:
以下香水含有Coumarin成份:
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